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Enabling Clinical and Translational Research

MMI Education & Training Topics



This web resource provides a comprehensive and easily-navigated overview of areas covered in the long-running widely-available MMI Courses & Workshops, in workshops offered by the Irish Clinical Research Infrastructure Network (ICRIN) and in modules and seminars forming part of MMI structured PhD programmes, the Clinician Scientist Fellowship Programme (CSFP) and the Clinical & Translational Research Scholars Programme (CTRSP).

In order to facilitate the use of this resource, modules and seminars are divided into themes: ‘Career Development’; ‘Clinical Research’; ‘Commercialisation of Research’; etc. Within each theme there is a short description of each module with the number of times it has run, the date on which it last ran and a link to a web page containing more information.

This overview brings together the offerings of MMI and its forerunner the DMMC, funded by the HEA under consecutive cycles of PRTLI, and of ICRIN funded by the HRB, HSE and Enterprise Ireland. In doing so, it illustrates a significant strand of collaborative education and training in clinical and translational research since 2003.

  • Those wishing to participate in MMI Education & Training can use this resource to identify whether courses in their areas of interest have run previously (you may also wish to visit the Forthcoming Courses & Workshops web page).
  • For potential collaborators in MMI education and training activities, this resource gathers what MMI has offered to date, and we hope provides ideas for the future.
  • For funders and other government agencies it illustrates the wealth of expertise assembled by MMI from multiple institutions and commercial partners to provide skills training to a wide audience of those who contribute to patient and disease oriented research and to the knowledge economy.
Contact education@molecularmedicineireland.ie if we can be of assistance.
 

Themed course & workshop areas

(click to expand):
 Career Development

The Road Less Travelled: A Career in Medical Education (CSFP Structured Training)
Description: The learning objectives of this seminar are: to understand the evolution of current approaches to medical education; to gain an understanding of the roles and responsibilities of a medical educator; to develop an insight into possible pathways to a part-time or full-time career in medical education.

Number of times it ran: 1

Date of the last run: 9 July 2009. Please click here for further information (Schedule and Learning Objectives for CSFP Structured Training Period 3).

Clinician Scientist Keynote Lecture Series (CSFP Structured Training)
Description: These lectures take place throughout the MMI Clinician Scientist Fellowship Programme Structured Training and Annual Scientific Meetings, given by leading Clinician Scientists from Ireland and internationally. As well as describing research, contributors cover career development aspects and provide insights on how to develop and sustain a research programme and secure funding.

Number of times it ran: Lecture series July 2008 to June 2010

Date of the last run: 25 June 2010. Please click here for further information

Funding Opportunities in Clinical & Translational Research (CSFP Structured Training)
Description: Presentations with opportunities for questions on how the Wellcome Trust supports translational research (Dr John Williams) and how the Health Research Board is building capacity in clinical and translational research (Dr Teresa Maguire).

Number of times it ran: 1

Date of the last run: 23 June 2010. Please click here for further information (Schedule and Learning Objectives for CSFP Structured Training Period 4).

SAFEMED Workshop: Leadership, Stress Regulation & Life Skills for Clinician Scientists (CSFP Structured Training)
Description: The objectives are to identify stress and to construct personal support plans to reduce negative effects and manage stress.

Number of times it ran: 1

Date of the last run: 9 July 2009. Please click here for further information (Schedule and Learning Objectives for CSFP Structured Training Period 4).
 
 Clinical Research

Introduction to Clinical Research and Good Clinical Practice (ICRIN)
Description: This course provides an overview for those interested in or working in clinical research, covering the terminology and conventions, the drug development pathway including the clinical trial process and issues of patient consent and safety. In addition, this course provides the mandatory training required for those working in investigational medicinal product trials.

Number of times it ran: 17

Date of the last run: 23 January 2013. Please click here for further information.

Clinical Research Insurance and Indemnity (ICRIN/State Claims Agency)
Description: The State Claims Agency and ICRIN organised this workshop to clarify the scope of the indemnity for clinical research offered by the Clinical Indemnity Scheme and to identify the respective roles of ICRIN, the Clinical Indemnity Scheme and Clinical Research Centres in insuring risks in clinical research.

Number of times it ran: 1

Date of the last run: 23 April 2009. Please click here for further information.

Impacting Healthcare Through Facilitating Clinical Studies of Medical Devices in Ireland (ICRIN)
Description: This introductory workshop is to give participants and overview of the clinical trial process, regulatory environment as well as experiences for commercialisation and clinical trials in Ireland. Representatives from Enterprise Ireland, Science Foundation Ireland, the Irish Platform for Patients Organisation, Science and Industry and the Irish Medical Device Association to speak about initiatives for the development of opportunities in Ireland for the Medical Device Industry.

Number of times it ran: 1

Date of the last run: 29 October 2009. Please click here for further information.

Health Technology Assessments and Re-Imbursement process for Medical Devices (ICRIN)
Description: This course is to give participants from academia, small and medium enterprises and indigeneous companies an overview of Health Technology Assessments and the re-imbursement process in Europe and Ireland.

Number of times it ran: 1

Date of the last run: 21-22 June 2010. Please click here for further information.
 
 
 Commercialisation of Research

Commercialisation of Research in Medicine and Health (CSFP Structured Training)
Description: This workshop covered the research commercialisation process (national policy, common university approaches, and how Technology Transfer Offices work with researchers) together with examples presented by academic and industry researchers and a presentation on the role of the Irish Medicines Board in bringing medicines and medical devices to the market and to patients.

Number of times it ran: 1

Date of the last run: 24 June 2010. Please click here for further information (Schedule and Learning Objectives for CSFP Structured Training Period 4).

Intellectual Property and Patents in Ireland's Smart Economy (CSFP Structured Training)
Description: This seminar provides an overview of patenting and the link with research. The concept of patenting leading to commercialisation is important not only in generating financial reward to inventors but also in ensuring that the benefits of technology are made available to society.

Number of times it ran: 1

Date of the last run: 8 July 2009. Please click here for further information (Schedule and Learning Objectives for CSFP Structured Training Period 3).
 
 
 Communicating Research & Using the Research Literature

Reading, Writing & Coping With the Biomedical Literature
Description: This course was designed for students to learn more about the process of getting their experimental data published and gain advice on how to keep up with the literature in their own and related fields. Participants had the opportunity to hone their writing skills by participating in small group discussions.

Number of times it ran: 1

Date of the last run: 5 September 2006. Please click here for further information.

Writing & Communication Skills (CSFP Structured Training)
Description: This 1-day interactive workshop covered the scientific publication process (including rankings, impact factors, citation rates, open access journals); the organisation of a scientific paper and the principles of good scientific writing (including abstract writing and the design of good figures and tables); the process of submitting a manuscript for publication (from referees to proofs and beyond); publication ethics (including areas of misconduct such as falsification, fabrication and plagiarism); how to craft effective scientific presentations (including slide and poster design).

Number of times it ran: 1

Date of the last run: 3 July 2008. Please click here for further information (Schedule and Learning Objectives for CSFP Structured Training Period 1).

Information Retrieval (CSFP Structured Training)
Description: This workshop covered how to access the scientific literature on the web and in databases, how to find and evaluate information effectively and efficiently, and how to manage the information collected or generated.

Number of times it ran: 1

Date of the last run: 22 September 2008. Please click here for further information (Schedule and Learning Objectives for CSFP Structured Training Period 2).

How to Review a Scientific Manuscript (CSFP Structured Training)
Description: This seminar identified the key features of manuscripts that indicate quality and the do’s and don’ts of reviewing, including how to provide constructive feedback to authors and how to communicate your views to editors.

Number of times it ran: 1

Date of the last run: 6 July 2009. Please click here for further information (Schedule and Learning Objectives for CSFP Structured Training Period 3).

Bibliometrics: Finding the Needle in the Information-Stack (CSFP Structured Training)
Description: This hands-on workshop covered how to define a search strategy in various e-resources available on the internet (using basic and advanced searches) and how to critically appraise publications retrieved and store these in local reference management software.

Number of times it ran: 1

Date of the last run: 7 July 2009. Please click here for further information (Schedule and Learning Objectives for CSFP Structured Training Period 3).

Communicating your Research Message: Sound Bites and Elevator Speeches (CSFP Structured Training)
Description: How to present your research and its value to a general audience and how to attract and maintain interest of the news media. Presented by Niall Kiely of Carr Communications.

Number of times it ran: 1

Date of the last run: 23 June 2010. Please click here for further information (Schedule and Learning Objectives for CSFP Structured Training Period 4).

Writing up your PhD (CSFP Structured Training)
Description: An interactive consideration of advanced aspects of the scientific publication process; how to approach scientific conferences; preparation for a research career in terms of key expectations for a PhD graduate; planning for writing the PhD thesis and understanding the function of the PhD viva.

Number of times it ran: 1

Date of the last run: 21 June 2010. Please click here for further information (Schedule and Learning Objectives for CSFP Structured Training Period 4).
 
 
 Conduct of Research

Integrity in Scientific Research (CSFP Structured Training)
Description: Understand ethical issues and obligations relating to access to confidential information obtained in a professional capacity. Be familiar with the obligations involved in collaboration with industrial collaborators and sponsors. Understand the need for high levels of integrity and transparency in interpreting research results. Understand the criteria that are used for determining authorship of research publications.

Number of times it ran: 1

Date of the last run: 4-5 July 2008. Please click here for further information (Schedule and Learning Objectives for CSFP Structured Training Period 1).

Grant Writing (CSFP Structured Training)
Description: The learning objectives of this seminar are: to be familiar with how grant systems work and how grants are assessed; to be able to identify appropriate support for your research and to initiate a grant submission.

Number of times it ran: 1

Date of the last run: 8 July 2009. Please click here for further information (Schedule and Learning Objectives for CSFP Structured Training Period 3).

Introduction to Project Management (CSFP Structured Training)
Description: Develop knowledge and understanding of best practice in project management and also acquire practical tips and tools of project management which can be applied to your own area of practice.

Number of times it ran: 1

Date of the last run: 25-26 September 2008. Please click here for further information (Schedule and Learning Objectives for CSFP Structured Training Period 2).

Research Creativity Workshop (CSFP Structured Training)
Description: An overview of the process, climate and culture required for creativity and innovation; including an introduction to practical tools relating to creativity and innovation and their implementation.

Number of times it ran: 1

Date of the last run: 22 June 2010. Please click here for further information (Schedule and Learning Objectives for CSFP Structured Training Period 4).
 
 
 Drug Discovery & Development

Drug Design and Delivery
Description: An overview and illustration of how the interaction of a drug target with a small molecule or a macromolecule can be optimised (in silico or in vitro) to develop a pharmaceutical or bio-pharmaceutical agent. Besides the optimisation of the affinity and selectivity of these drug candidates for the therapeutic target, other key issues to be considered at the drug discovery & development stages, such as absorption, distribution, metabolism and excretion (ADME) properties, drug delivery, protection of the intellectual property and regulatory affairs are also introduced.

Number of times it ran: 4

Date of the last run: 12-13 October 2009. Please click here for further information.

Molecules to Medicines: How Biopharma Delivers (Lecture Course)
Description: This Course will be of interest to research students, academic staff and clinicians, whether contemplating a career in industry or doing translational research in academia. The lectures provide an overview of biopharmaceutical discovery, development and manufacturing, delivered by key industry staff. The course and workshop were originally developed with key staff from Weth Pharmaceuticals: Dr. Davinder Gill, Dr. Mark Leonard & Dr. Brendan Hughes.

Number of times it ran: 8

Date of the last run: 6 November 2013. Please click here for further information


Molecules to Medicines: How Biopharma Delivers (Workshop)
Description: This MMI/Pfizer 1-day workshop, for 24 participants, comprises discussion of key issues arising during biopharmaceutical discovery, development, and manufacturing. It will include breakout group discussion of specially devised problem sets. It is followed by a tour of the Pfizer Grange Castle Facility.

Number of times it ran
: 8

Date of the last run: 7 November 2013. Please click here for further information
 
 
 Genomics / Epigenetics

Human Disease Genomics: SNPs, GWAS and Next-Gen Sequencing (Lecture Course)
Description: This course aims to introduce researchers to key strategic considerations in designing and performing gene-mapping studies. A one-day lecture course introduces SNPs and haplotypes, genetic association and study design, genome-wide association studies and the use of next generation sequencing technology. This course ran previously as Population Genetics & SNP Analysis.

Number of times it ran: 5

Date of the last run: 27 June 2012. Please click here for further information

Human Disease Genomics: SNPs, GWAS and Next-Gen Sequencing (Workshop)
Description: This practical workshop follows on from the lecture course. In 2010 it was delivered by a representative from the Ensembl project (http://www.ensembl.org). The Ensembl project provides a comprehensive and integrated source of annotation of genome sequences. The workshop provided participants with guided hands-on experience in the use of the Ensembl genome browser and the necessary background information to make best use of this online resource. There was a focus on the analysis of genetic variation that complemented the lecture course material.

Number of times it ran: 5

Date of the last run: 28 June 2012. Please click here for further information.

Unravelling Chromatin & The Role of Epigenetics in Disease
Description: Day one covered chromatin structure and the principles of epigenetics. Lectures detailed the covalent modifications of DNA and histones, the techniques used to determine epigenetic modification, and the principles and experimental application of miRNA and siRNA technology. Day two focused on epigenetics in development and disease, and the applications of epigenetics in answering specific research questions.

Number of times it ran: 1

Date of the last run: 25 - 26 April 2006. Please click here for further information.

Epigenetics: From Mechanisms to Medicines (International Workshop)
Description: This workshop, open to an international audience, concentrates on the latest developments worldwide in: study of epigenetic mechanisms; techniques and technologies used; application of knowledge of epigenetic mechanisms in the clinic. It is designed to encapsulate current basic and clinical research and provide a glimpse of future potential for an audience of bioscientists and physicians with an interest in epigenetics.

Number of times it ran: 1

Date of the last run: 25-26 June 2007. Please click here for further information.
 
 
 Molecular Biology/Genetics in Translational Research

Molecular Cell Biology in Action
Description: This course covers the molecular processes and interactions inside and between cells. Lecturers describe the experimental study of these processes, and how this impacts on knowledge and treatment of disease.

Number of times it ran: 3

Date of the last run: 2 November - 14 December 2005. Please click here for further information.

The Biology Behind the Disease: Molecular Biology Lectures and Self-Directed Learning Assignment (CSFP Structured Training)
Description: Lectures provide an understanding of concepts and techniques in molecular and cell biology and genetics. Self-directed learning assignments promote critical thinking and communication across the spectrum from the basic molecular biology of cellular processes to the physiological manifestations of disease (including experience in collaborative working, critical evaluation of recently published research papers and presenting research).

Number of times it ran: 1

Date of the last run: 16-18 and 23-24 September 2008. Please click here for further information (Schedule and Learning Objectives for CSFP Structured Training Period 2).
 
 
 Techniques and Technologies: Overview

Techniques and Strategies in Molecular Medicine
Description: This course, running over 2 full days, is designed to give bioscientists and clinicians a broad overview of research techniques and their application. Basic molecular biology laboratory experience is assumed, but you should not need prior knowledge of the techniques covered in the course.

Number of times it ran: 10

Date of the last run: 3 - 4 December 2013. Please click here for further information.

Model Systems in Biomedical Research: Scientific Breakthroughs
Description: This course aims to demonstrate the power of model experimental systems in biomedical research by highlighting examples of major scientific breakthroughs achieved in various model organisms. The course brings together Irish and international experts who utilise model experimental systems in their own research. Each lecture also includes a Technical Spotlight that describes a powerful experimental tool developed in the model system.

Number of times it ran
: 1

Date of the last run: 23 March - 18 May 2006. Please click here for further information.

Animal Models of Disease: Relevance to study of human pathophysiology (CSFP Structured Training)
Description: Understand the concepts/considerations in the development of animal models for diseases including schizophrenia, diabetes, and pulmonary disease. Understand studies directed at elucidating disease pathogenesis as well as development of therapeutic approaches.

Number of times it ran:
1

Date of the last run: 19 September 2008. Please click here for further information (Schedule and Learning Objectives for CSFP Structured Training Period 2).

Core Technology Facilities (CSFP Structured Training)
Description: Guided tours and demonstrations of core technology facilities: mass spectrometry for proteomics; confocal imaging; specific pathogen free facility and in vivo imaging; high throughput genomics; electron microscopy. Hosted by the UCD Conway Institute.

Number of times it ran:
1

Date of the last run: 19 September 2008. Please click here for further information (Schedule and Learning Objectives for CSFP Structured Training Period 2).

Techniques Workshops (CSFP Structured Training)
Description: Understand the principles and applications of various technologies and techniques in interactive sessions that encourage discussion: Flow Cytometry; Microarray; Real Time PRC; Immunohistochemistry/ immunocytochemistry; basic molecular biology techniques; DNA/RNA/protein isolation.

Number of times the course ran
: 1

Date of the last run: 9 July 2009. Please click here for further information (Schedule and Learning Objectives for CSFP Structured Training Period 3).
 
 
 Techniques and Technologies: Specific Areas

Bioinformatics Workshop (CSFP Structured Training)
Description: Participants will be made aware of freely available web-based tools and databases; understand how nucleic acid and protein sequence data is obtained and analysed; understand the principles of sequence search and alignment; develop skills in utilising online databases and in interpreting data; appreciate how bioinformatics can be used to solve problems and generate knowledge.

Number of times it ran:
1

Date of the last run: 16-18 September 2008. Please click here for further information (Schedule and Learning Objectives for CSFP Structured Training Period 2).

PYTHON Programming for Bioinformatics Analysis
Description: This course provided a hands-on introduction to Python programming, designed for first-year PhD students in bioinformatics, but also open to others with an interest in using Python. Python is an interpreted, interactive, object-oriented programming language.

Number of times it ran: 1

Date of the last run: 29 November - 2 December 2004. Please click here for further information.

Biostatistics (MMI/HRB CRF Galway)
Description: The aim of the workshop is to provide participants with an overview of fundamental biostatistical methods, an understanding of the key concept of variability and a practical working knowledge of the statistical techniques they are likely to encounter in applied medical research. Techniques covered include study design, analysing one and two sample problems (independent and dependent data) through interval estimation and hypothesis testing approaches, comparing three or more samples (analysis of variance), regression problems, survival analysis, logistic regression and sample size calculations. Each session includes lectures and computer based practical work.

Number of times it ran:
1

Date of the last run: 6-10 July 2009. Please click here for further information.

Thermodynamics of Membrane Transport Physiology
Description: Lectures with hands-on computer modelling of membrane transport, pharmacokinetics, and pharmacodynamics. Lectures cover: Basic thermodynamics: flow-force relations; Isothermal diffusion; Diffusion potentials; Water transport; Active transport; Coupled transport. A hands-on workshop introduces the use of Berkeley Madonna for modelling in Physiology and Chemistry, and PK/PD modelling with Berkeley Madonna.

Number of times it ran:
1

Date of the last run: 21-25 February 2005. Please click here for further information.

Microarray Experimental Design
Description: Expression microarrays produce large amounts of data and are relatively expensive. Therefore, it is essential that projects involving microarrays are carefully considered from the outset. What biological question(s) are you asking? What are the array types available and how do they differ? How many arrays will you need? What quantity and quality of RNA sample is required? How many replicates? Should you pool samples? What are the sources of variation? How can you minimise and control for non-informative experimental variation? What are the statistical issues that you need to be aware of at the experimental design stage? Time spent in designing a good microarray experiment will help to minimise difficulties in data analysis and reduce costly repeats. This course comprises lectures covering the basics of designing a microarray project. and a breakout session to discuss participants experimental design issues.

Number of times it ran:
1

Date of the last run: 17 April 2007. Please click here for further information.

Microarray Data Analysis
Description: Expression microarray experiments generate large amounts of data, the analysis and interpretation of which is not trivial. Lectures covering important considerations in normalisation, analysis and interpretation of microarray data are followed by a hands-on practical workshop. The practical workshop utilises Bioconductor microarray data analysis software, part of the open source R statistical package, to highlight the principles of good analysis. We recognise that course participants may be using various commercial and non-commercial software packages to analyse their microarray data, but in the interests of time and clarity we have selected Bioconductor as the hands-on teaching tool during this course.

Number of times it ran:
2

Date of the last run: 10 May 2007. Please click here for further information.

Proteomics: Methods & Applications
Description: The wealth of genomic data now available provides us with the opportunity to perform comprehensive protein profiling studies of complex biological systems. Application of the science of proteomics will result in new insights into cellular functions in health and disease, and lead to the discovery of new diagnostic agents and therapeutic targets. This course is designed to give an overview of the main workflows that are currently being used for protein profiling: 1) two-dimensional gel electrophoresis 2)liquid chromatography coupled either on- or off-line to mass spectrometry 3) protein and antibody micro-arrays. The course is designed to equip participants with the level of knowledge required to assess the potential applicability of proteomics to their research.

Number of times the course ran
: 3

Date of the last run: 30 May - 13 June 2006. Please click here for further information.  

Magnetic Resonance Imaging Applications in Research (MMI/HRB Centre for Advanced Medical Imaging)
Description: The purpose of this workshop is to describe the potential of Magnetic Resonance Imaging (MRI) as a research tool in basic and clinical research. MRI allows high resolution imaging of structures and functions in the body without the use of ionising radiation. The high acceptability and low risk of MRI make it very suitable for imaging patient and volunteer cohorts in research studies. Applications include tumour imaging, investigation of cardiovascular function and imaging of neural activity. MRI techniques can follow a concept from an animal model right through to human clinical applications.

Number of times the course ran:
1

Date of the last run: 17 September 2009. Please click here for further information.

Bioengineering (CSFP Structured Training)
Description: An introduction to the basics of biomechanics and biomechanical engineering , using both experimental and modelling methods, in the context of biological cells, tissues, systems and medical implants and devices.

Number of times the course ran: 1

Date of the last run: 8 July 2009. Please click here for further information (Schedule and Learning Objectives for CSFP Structured Training Period 3).

Introduction to Data Analysis
Description: This intensive 2-day practical, hands-on course for researchers in biological and clinical science is designed to provide an overview of data types, simple statistical analysis techniques, and study design, with particular emphasis on the assumptions underlying these techniques.

Number of times the course ran
: 2

Date of the last run: 8 - 9 May 2013. Please click here for further information
 
 
 Translational Research: Specific Areas

Immunobiology
Description: At the end of this course, participants should be familiar with the basic terms and concepts of innate and adaptive immunity and conversant with the names and functions of the main organs, cells, molecules and genes involved in initiating and mediating immune responses. They should be able to explain fundamental immunological concepts and discuss the roles of functional components of the immune system including acute phase proteins, complement, haematopoietic cells, immunoglobulins and cytokines in protecting against disease. They should also understand some basic concepts of immunological dysregulation seen in inflammatory and autoimmune diseases, allergy, malignancy and immunopathogenesis.

Number of times it ran:
4

Date of last run: 10 January - 7 March 2007. Please click here for further information.

Neurobiology
Description: Contents include: Neurotransmitters; Neurophysiology; Dementia; Parkinson's disease; Multiple sclerosis; Motor Neurone disease; Disorders of the Peripheral Nervous System; Degeneration and Regeneration of the Central Nervous System; Molecular Biology of Memory; Genetics of Psychiatric Diseases; Triplet Repeat Expansion and Human Disease.

Number of times it ran:
1

Date of the last run: 4-25 February 2004. Please click here for further information.

Introductory Coronary Artery Disease
Description: The course provides an introduction to coronary artery disease and aims to strike a balance between clinical and research aspects. It is appropriate for those new to coronary artery disease treatment and research, for non-specialist scientists and clinicians wanting an introduction to this area, and as an introduction to the Advanced Coronary Artery Disease course.

Number of times it ran: 1

Date of the last run : 18-19 October 2004. Please click here for further information.

Advanced Coronary Artery Disease
Description: The course aims to strike a balance between clinical and research aspects of coronary artery disease. The following themes are covered: atherosclerosis; risk factors; disease; platelets; intervention. A basic knowledge is assumed.

Number of times it ran:
1

Date of the last run: 16-19 November 2004. Please click here for further information.

Cancer Biology to Cancer Medicine
Description: This course is designed to provide an overview of the main cellular and molecular processes involved in cancer development and progression, defining these processes in detail in a selected number of human malignancies. It demonstrates how an increasing knowledge of cancer development and progression at the molecular level is providing a conduit for the application of molecular medicine in cancer diagnostics and cancer therapeutics.

Number of times it ran: 3

Date of the last run: 24-26 May 2006. Please click here for further information.
 
 Core Modules October 2011

Integrated Pharmacology (CTRSP Structured Training)
Description: The learning objectives of this seminar are:

Number of times it ran: 1

Date of the last run: . Please click here for further information